Sideroblastic and megaloblastic change
نویسندگان
چکیده
منابع مشابه
Sideroblastic and megaloblastic change.
Introduction THE simultaneous occurrence in the bone marrow of megaloblasts and ring-sideroblasts may result from a variety of causes. In a series of seventy patients with sideroblastic anaemia, MacGibbon and Mollin (1965) observed megaloblastic change in 544O of cases of primary sideroblastic anaemia, and in 74YO of cases of secondary sideroblastic anaemia. The megaloblastic change was attribu...
متن کاملSideroblastic anemia in multiple myeloma: a preleukemic change.
In a 10-yr observation period, 75 patients with multiple myeloma have been studied, and 55 of these were treated daily with low dose melphalan by mouth. Of these, four developed sideroblastic anemia, manifested by anemia, thrombocytopenia, aniso-poikilocytosis, and hypochromic stippled cells in the blood, and ringed sideroblasts in the bone marrow. In two patients, this complication occurred af...
متن کاملSideroblastic anemia.
When first defined 50 years ago, sideroblastic anemia (SA) was already recognized to occur in heterogeneous settings, including as familial or acquired disease. The spectrum of SA has since become considerably expanded with respect to distinct clinical phenotypes as well as discrete causes. The singular feature that typifies all forms of SA and is required for initial diagnosis is the presence ...
متن کاملMegaloblastic anemia of pregnancy: characteristics of pure megaloblastic anemia and megaloblastic anemia associated with iron deficiency.
LTHOUGH megaboblastic anemia of pregnancy is considered mainly as a folic acid deficiency anemia, since this vitamin induces remission in most cases, its mechanism of production is still obscure. Dietary deficiency has been claimed to be the principal cause. However, this anemia has been observed in well-to-do women whose diet was satisfactory. Some other factors such as gastrointestinal upset,...
متن کاملRing sideroblasts and sideroblastic anemias.
Ring sideroblasts Ring sideroblasts are erythroblasts with iron-loaded mitochondria visualized by Prussian blue staining (Perls’ reaction) as a perinuclear ring of blue granules (Figures 1D and 2C). The International Working Group on Morphology of Myelodysplastic Syndrome (IWGM-MDS) recommended that ring sideroblasts be defined as erythroblasts in which there are a minimum of five siderotic gra...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Postgraduate Medical Journal
سال: 1976
ISSN: 0032-5473
DOI: 10.1136/pgmj.52.606.241